diff --git a/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm b/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm
index 684133b0dc9..6aed4566a99 100644
--- a/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm
+++ b/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm
@@ -47,13 +47,13 @@
 		var/best_stat = get_key_by_index(damage_stats,1)
 		switch(best_stat)
 			if(BRUTE)
-				M.adjustBruteLoss(removed*5)
+				M.adjustBruteLoss(-removed*5)
 			if(BURN)
-				M.adjustFireLoss(removed*5)
+				M.adjustFireLoss(-removed*5)
 			if(TOX)
-				M.adjustToxLoss(removed*5)
+				M.adjustToxLoss(-removed*5)
 			if(OXY)
-				M.adjustOxyLoss(removed*5)
+				M.adjustOxyLoss(-removed*5)
 
 	M.make_jittery(removed)
 	M.add_chemical_effect(CE_STABLE)
@@ -663,7 +663,7 @@
 	var/list/suppressing_reagents = list() // List of reagents that suppress the withdrawal effects, with the key being the reagent and the vlue being the minimum dosage required to suppress.
 
 	fallback_specific_heat = 1.5
-	
+
 /datum/reagent/mental/affect_blood(var/mob/living/carbon/human/H, var/alien, var/removed)
 
 	if(!istype(H) || max_dose < min_dose || (world.time < data && volume > removed) || messagedelay == -1)
@@ -1116,10 +1116,14 @@
 	var/chance = dose*removed
 	if(M.bodytemperature < 170)
 		chance = (chance*4) + 5
+		M.adjustBrainLoss(-30 * removed)
+	else
+		M.adjustBrainLoss(-10 * removed)
+
 	if(prob(chance))
 		M.cure_trauma_type(pick(curable_traumas))
 
-	M.adjustBrainLoss(10*removed)
+
 
 //Things that are not cured/treated by medication:
 //Gerstmann Syndrome
diff --git a/html/changelogs/burgerbb - BRAIN DAMAGE.yml b/html/changelogs/burgerbb - BRAIN DAMAGE.yml
new file mode 100644
index 00000000000..d0e3c17b5bf
--- /dev/null
+++ b/html/changelogs/burgerbb - BRAIN DAMAGE.yml	
@@ -0,0 +1,37 @@
+################################
+# Example Changelog File
+#
+# Note: This file, and files beginning with ".", and files that don't end in ".yml" will not be read. If you change this file, you will look really dumb.
+#
+# Your changelog will be merged with a master changelog. (New stuff added only, and only on the date entry for the day it was merged.)
+# When it is, any changes listed below will disappear.
+#
+# Valid Prefixes: 
+#   bugfix
+#   wip (For works in progress)
+#   tweak
+#   soundadd
+#   sounddel
+#   rscadd (general adding of nice things)
+#   rscdel (general deleting of nice things)
+#   imageadd
+#   imagedel
+#   maptweak
+#   spellcheck (typo fixes)
+#   experiment
+#   balance
+#################################
+
+# Your name.  
+author: BurgerBB
+
+# Optional: Remove this file after generating master changelog.  Useful for PR changelogs that won't get used again.
+delete-after: True
+
+# Any changes you've made.  See valid prefix list above.
+# INDENT WITH TWO SPACES.  NOT TABS.  SPACES.
+# SCREW THIS UP AND IT WON'T WORK.
+# Also, all entries are changed into a single [] after a master changelog generation. Just remove the brackets when you add new entries.
+# Please surround your changes in  double quotes ("), as certain characters otherwise screws up compiling. The quotes will not show up in the changelog.
+changes: 
+  - bugfix: "Fixes Mannitol and Epinephrine killing people instead of healing them."