diff --git a/code/modules/reagents/Chemistry-Recipes.dm b/code/modules/reagents/Chemistry-Recipes.dm
index db70a92e9fb..a0d7f1fd643 100644
--- a/code/modules/reagents/Chemistry-Recipes.dm
+++ b/code/modules/reagents/Chemistry-Recipes.dm
@@ -298,8 +298,8 @@
 	name = "Tricordrazine"
 	id = "tricordrazine"
 	result = /decl/reagent/tricordrazine
-	required_reagents = list(/decl/reagent/inaprovaline = 1, /decl/reagent/dylovene = 1)
-	result_amount = 2
+	required_reagents = list(/decl/reagent/water = 1, /decl/reagent/inaprovaline = 1, /decl/reagent/dylovene = 1)
+	result_amount = 3
 
 /datum/chemical_reaction/alkysine
 	name = "Alkysine"
diff --git a/html/changelogs/tricordrazine_removal.yml b/html/changelogs/tricordrazine_removal.yml
new file mode 100644
index 00000000000..b0c1ab259b9
--- /dev/null
+++ b/html/changelogs/tricordrazine_removal.yml
@@ -0,0 +1,6 @@
+author: SleepyGemmy
+
+delete-after: True
+
+changes:
+  - tweak: "Tricordrazine now needs water to react, which makes Tricordrazine no longer mix in your bloodstream if you inject inaprovaline and dylovene at the same time."
\ No newline at end of file