diff --git a/code/modules/antagonists/blob/blobstrains/energized_jelly.dm b/code/modules/antagonists/blob/blobstrains/energized_jelly.dm
index 349ca1b5722..9fa5ed9ab96 100644
--- a/code/modules/antagonists/blob/blobstrains/energized_jelly.dm
+++ b/code/modules/antagonists/blob/blobstrains/energized_jelly.dm
@@ -22,7 +22,7 @@
 	B.take_damage(damage, BURN, ENERGY)
 
 /datum/reagent/blob/energized_jelly
-	name = "Energized Jelly"
+	name = "Energized Blob Jelly"
 	taste_description = "gelatin"
 	color = "#EFD65A"
 
diff --git a/code/modules/reagents/chemistry/reagents.dm b/code/modules/reagents/chemistry/reagents.dm
index 12338f3645b..13abd53f1b6 100644
--- a/code/modules/reagents/chemistry/reagents.dm
+++ b/code/modules/reagents/chemistry/reagents.dm
@@ -17,7 +17,7 @@ GLOBAL_LIST_INIT(name2reagent, build_name2reagent())
 /// A single reagent
 /datum/reagent
 	/// datums don't have names by default
-	var/name = "Reagent"
+	var/name = ""
 	/// nor do they have descriptions
 	var/description = ""
 	///J/(K*mol)
diff --git a/code/modules/reagents/chemistry/reagents/drink_reagents.dm b/code/modules/reagents/chemistry/reagents/drink_reagents.dm
index ad377282472..bac6907088b 100644
--- a/code/modules/reagents/chemistry/reagents/drink_reagents.dm
+++ b/code/modules/reagents/chemistry/reagents/drink_reagents.dm
@@ -431,7 +431,7 @@
 /datum/reagent/consumable/roy_rogers
 	name = "Roy Rogers"
 	description = "A sweet fizzy drink."
-	color = "#53090B" 
+	color = "#53090B"
 	quality = DRINK_GOOD
 	taste_description = "fruity overlysweet cola"
 	glass_icon_state = "royrogers"
@@ -439,7 +439,7 @@
 	glass_desc = "90% sugar in a glass."
 	chemical_flags = REAGENT_CAN_BE_SYNTHESIZED
 
-/datum/reagent/consumable/roy_roger/on_mob_life(mob/living/carbon/M, delta_time, times_fired)
+/datum/reagent/consumable/roy_rogers/on_mob_life(mob/living/carbon/M, delta_time, times_fired)
 	M.Jitter(6 * REM * delta_time) //not as strong as coffe, still this is a lot of sugar
 	M.adjust_drowsyness(-5 * REM * delta_time)
 	M.adjust_bodytemperature(-5 * REM * TEMPERATURE_DAMAGE_COEFFICIENT * delta_time, M.get_body_temp_normal())
@@ -805,7 +805,7 @@
 /datum/reagent/consumable/cinderella
 	name = "Cinderella"
 	description = "Most definitely a fruity alcohol cocktail to have while partying with your friends."
-	color = "#FF6A50" 
+	color = "#FF6A50"
 	quality = DRINK_VERYGOOD
 	taste_description = "sweet tangy fruit"
 	glass_icon_state = "cinderella"
@@ -1171,7 +1171,7 @@
 /datum/reagent/consumable/agua_fresca
 	name = "Agua Fresca"
 	description = "A refreshing watermelon agua fresca. Perfect on a day at the holodeck."
-	color = "#D25B66" 
+	color = "#D25B66"
 	quality = DRINK_VERYGOOD
 	taste_description = "cool refreshing watermelon"
 	glass_icon_state = "aguafresca"
diff --git a/code/modules/reagents/chemistry/reagents/medicine_reagents.dm b/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
index 259e4219589..18524f63ddd 100644
--- a/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
+++ b/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
@@ -7,7 +7,6 @@
 // where all the reagents related to medicine go.
 
 /datum/reagent/medicine
-	name = "Medicine"
 	taste_description = "bitterness"
 	failed_chem = /datum/reagent/impurity/healing/medicine_failure
 
diff --git a/code/modules/reagents/chemistry/reagents/other_reagents.dm b/code/modules/reagents/chemistry/reagents/other_reagents.dm
index 75eb49fdcba..589c5ec4fc1 100644
--- a/code/modules/reagents/chemistry/reagents/other_reagents.dm
+++ b/code/modules/reagents/chemistry/reagents/other_reagents.dm
@@ -135,6 +135,7 @@
 		src.data |= data.Copy()
 
 /datum/reagent/vaccine/fungal_tb
+	name = "Vaccine (Fungal Tuberculosis)"
 
 /datum/reagent/vaccine/fungal_tb/New(data)
 	. = ..()
diff --git a/code/modules/reagents/chemistry/reagents/toxin_reagents.dm b/code/modules/reagents/chemistry/reagents/toxin_reagents.dm
index 1abba7c6719..8cc7f1a13cd 100644
--- a/code/modules/reagents/chemistry/reagents/toxin_reagents.dm
+++ b/code/modules/reagents/chemistry/reagents/toxin_reagents.dm
@@ -456,7 +456,7 @@
 	..()
 
 /datum/reagent/toxin/fakebeer //disguised as normal beer for use by emagged brobots
-	name = "Beer"
+	name = "Beer...?"
 	description = "A specially-engineered sedative disguised as beer. It induces instant sleep in its target."
 	color = "#664300" // rgb: 102, 67, 0
 	metabolization_rate = 1.5 * REAGENTS_METABOLISM
@@ -790,11 +790,11 @@
 	toxpwr = 0
 	chemical_flags = REAGENT_CAN_BE_SYNTHESIZED|REAGENT_NO_RANDOM_RECIPE
 
-/datum/reagent/medicine/sodium_thiopental/on_mob_add(mob/living/L, amount)
+/datum/reagent/toxin/sodium_thiopental/on_mob_add(mob/living/L, amount)
 	. = ..()
 	ADD_TRAIT(L, TRAIT_ANTICONVULSANT, name)
 
-/datum/reagent/medicine/sodium_thiopental/on_mob_delete(mob/living/L)
+/datum/reagent/toxin/sodium_thiopental/on_mob_delete(mob/living/L)
 	. = ..()
 	REMOVE_TRAIT(L, TRAIT_ANTICONVULSANT, name)
 
diff --git a/code/modules/unit_tests/_unit_tests.dm b/code/modules/unit_tests/_unit_tests.dm
index f5de816e136..f1088eb1477 100644
--- a/code/modules/unit_tests/_unit_tests.dm
+++ b/code/modules/unit_tests/_unit_tests.dm
@@ -97,6 +97,7 @@
 #include "reagent_id_typos.dm"
 #include "reagent_mod_expose.dm"
 #include "reagent_mod_procs.dm"
+#include "reagent_names.dm"
 #include "reagent_recipe_collisions.dm"
 #include "resist.dm"
 #include "say.dm"
diff --git a/code/modules/unit_tests/reagent_names.dm b/code/modules/unit_tests/reagent_names.dm
new file mode 100644
index 00000000000..540dead0d3b
--- /dev/null
+++ b/code/modules/unit_tests/reagent_names.dm
@@ -0,0 +1,15 @@
+/// Test that all reagent names are different in order to prevent #65231
+/datum/unit_test/reagent_names
+
+/datum/unit_test/reagent_names/Run()
+	var/used_names = list()
+
+	for (var/datum/reagent/reagent as anything in subtypesof(/datum/reagent))
+		var/name = initial(reagent.name)
+		if (!name)
+			continue
+
+		if (name in used_names)
+			Fail("[used_names[name]] shares a name with [reagent] ([name])")
+		else
+			used_names[name] = reagent