diff --git a/code/__DEFINES/reagents.dm b/code/__DEFINES/reagents.dm
index e25d66686e5..18b41f0a058 100644
--- a/code/__DEFINES/reagents.dm
+++ b/code/__DEFINES/reagents.dm
@@ -28,6 +28,7 @@
 #define ADD_REAGENT		2	// reagent added
 #define REM_REAGENT		3	// reagent removed (may still exist)
 #define CLEAR_REAGENTS	4	// all reagents were cleared
+#define REACT_REAGENTS	5	// a reaction occured
 
 #define MIMEDRINK_SILENCE_DURATION 30  //ends up being 60 seconds given 1 tick every 2 seconds
 //used by chem masters and pill presses
diff --git a/code/modules/reagents/chemistry/holder.dm b/code/modules/reagents/chemistry/holder.dm
index 1f02f9d2a54..5a67938bdf8 100644
--- a/code/modules/reagents/chemistry/holder.dm
+++ b/code/modules/reagents/chemistry/holder.dm
@@ -516,6 +516,7 @@
 							ME2.name = "used slime extract"
 							ME2.desc = "This extract has been used up."
 
+			my_atom?.on_reagent_change(REACT_REAGENTS)
 			selected_reaction.on_reaction(src, multiplier)
 			reaction_occurred = 1