diff --git a/code/modules/mob/living/basic/farm_animals/bee/_bee.dm b/code/modules/mob/living/basic/farm_animals/bee/_bee.dm
index 4f0fd61f1ba..75d09831358 100644
--- a/code/modules/mob/living/basic/farm_animals/bee/_bee.dm
+++ b/code/modules/mob/living/basic/farm_animals/bee/_bee.dm
@@ -197,6 +197,29 @@
 	AddElement(/datum/element/venomous, beegent.type, injection_range, thrown_effect = TRUE)
 	generate_bee_visuals()
 
+/// Picks a random toxin and assigns it to the bee
+/mob/living/basic/bee/proc/assign_random_toxin_reagent(respect_can_synth = TRUE)
+	var/list/toxin_pool = typesof(/datum/reagent/toxin)
+	var/datum/reagent/toxin
+	var/sanity = 0
+
+	do
+		if(sanity > 20 || !length(toxin_pool))
+			toxin = pick(/datum/reagent/toxin, /datum/reagent/toxin/histamine, /datum/reagent/toxin/venom)
+			respect_can_synth = FALSE // in case someone removes cansynth from all of the above for some goofy reason
+		else
+			toxin = pick_n_take(toxin_pool)
+			sanity += 1
+	while(respect_can_synth && !(toxin::chemical_flags & REAGENT_CAN_BE_SYNTHESIZED))
+
+	assign_reagent(GLOB.chemical_reagents_list[toxin])
+
+/mob/living/basic/bee/mutate()
+	. = ..()
+	if(!.)
+		assign_random_toxin_reagent()
+		. = TRUE
+
 /mob/living/basic/bee/queen
 	name = "queen bee"
 	desc = "She's the queen of bees, BZZ BZZ!"
@@ -212,8 +235,7 @@
 
 /mob/living/basic/bee/toxin/Initialize(mapload)
 	. = ..()
-	var/datum/reagent/toxin = pick(typesof(/datum/reagent/toxin))
-	assign_reagent(GLOB.chemical_reagents_list[toxin])
+	assign_random_toxin_reagent()
 
 /// A bee which despawns after a short amount of time (beespawns?)
 /mob/living/basic/bee/timed
diff --git a/code/modules/research/xenobiology/vatgrowing/samples/_micro_organism.dm b/code/modules/research/xenobiology/vatgrowing/samples/_micro_organism.dm
index 0b73e235140..94f12230950 100644
--- a/code/modules/research/xenobiology/vatgrowing/samples/_micro_organism.dm
+++ b/code/modules/research/xenobiology/vatgrowing/samples/_micro_organism.dm
@@ -29,6 +29,8 @@
 	var/atom/resulting_atom
 	///The number of resulting atoms
 	var/resulting_atom_count = 1
+	/// Counts how many times this cell line has been grown successfully
+	VAR_FINAL/grow_count = 0
 
 ///Handles growth of the micro_organism. This only runs if the micro organism is in the growing vat. Reagents is the growing vats reagents
 /datum/micro_organism/cell_line/proc/handle_growth(obj/machinery/vatgrower/vat)
@@ -75,26 +77,11 @@
 
 ///Called once a cell line reaches 100 growth. Then we check if any cell_line is too far so we can perform an epic fail roll
 /datum/micro_organism/cell_line/proc/finish_growing(obj/machinery/vatgrower/vat)
-	var/risk = 0 //Penalty for failure, goes up based on how much growth the other cell_lines have
-
-	for(var/datum/micro_organism/cell_line/cell_line in vat.biological_sample.micro_organisms)
-		if(cell_line == src) //well duh
-			continue
-		if(cell_line.growth >= VATGROWING_DANGER_MINIMUM)
-			risk += cell_line.growth * 0.6 //60% per cell_line potentially. Kryson should probably tweak this
 	playsound(vat, 'sound/effects/splat.ogg', 50, TRUE)
-	if(rand(1, 100) < risk) //Fail roll!
-		fuck_up_growing(vat)
-		. = FALSE
-	else
-		succeed_growing(vat)
-		. = TRUE
+	succeed_growing(vat)
 	SEND_SIGNAL(vat.biological_sample, COMSIG_SAMPLE_GROWTH_COMPLETED)
-
-/datum/micro_organism/cell_line/proc/fuck_up_growing(obj/machinery/vatgrower/vat)
-	vat.visible_message(span_warning("The biological sample in [vat] seems to have dissipated!"))
-	if(prob(50))
-		new /obj/effect/gibspawner/generic(get_turf(vat)) //Spawn some gibs.
+	grow_count += 1
+	return TRUE
 
 /datum/micro_organism/cell_line/proc/succeed_growing(obj/machinery/vatgrower/vat)
 	do_smoke(0, vat, vat.loc)
@@ -103,13 +90,13 @@
 		ADD_TRAIT(thing, TRAIT_VATGROWN, "vatgrowing")
 		vat.visible_message(span_nicegreen("[thing] pops out of [vat]!"))
 		//We maybe add some color. the chance is static for now, but idewally we would be able to manipulate it in the future.
-		if(prob(CYTO_SHINY_CHANCE))
-			if(isbasicmob(thing))
-				var/mob/living/basic/vat_creature = thing
-				//if the mob has a special mutation interaction don't do any other mutations. Once we add more mutations that are stackable with shiny we should probably roll for each type independently.
-				if(vat_creature.mutate())
-					return
-			mutate_color(thing)
+		if(prob(CYTO_SHINY_CHANCE) && isbasicmob(thing))
+			var/mob/living/basic/vat_creature = thing
+			//if the mob has a special mutation interaction don't do any other mutations.
+			// Once we add more mutations that are stackable with shiny we should probably roll for each type independently.
+			if(!vat_creature.mutate())
+				mutate_color(thing)
+
 		SEND_SIGNAL(vat.biological_sample, COMSIG_SAMPLE_DEPOSITED, thing)
 
 ///Overriden to show more info like needs, supplementary and supressive reagents and also growth.
diff --git a/code/modules/research/xenobiology/vatgrowing/samples/cell_lines/common.dm b/code/modules/research/xenobiology/vatgrowing/samples/cell_lines/common.dm
index 1aba2f34578..87e6fce25e9 100644
--- a/code/modules/research/xenobiology/vatgrowing/samples/cell_lines/common.dm
+++ b/code/modules/research/xenobiology/vatgrowing/samples/cell_lines/common.dm
@@ -468,7 +468,8 @@
 		/datum/reagent/wittel = 10, //stupid rare
 		/datum/reagent/medicine/omnizine/protozine = 5,
 		/datum/reagent/plasma_oxide = 3,
-		/datum/reagent/clf3 = 1)//since this is also chemistry it's worth near nothing
+		/datum/reagent/clf3 = 1,
+	)//since this is also chemistry it's worth near nothing
 
 	suppressive_reagents = list(//generics you would regularly put in a vat kill abberant residue
 		/datum/reagent/consumable/nutriment/peptides = -6,
@@ -482,12 +483,20 @@
 	resulting_atom = pick(/mob/living/basic/creature, /mob/living/basic/migo, /mob/living/basic/blankbody) //i looked myself, pretty much all of them are reasonably strong and somewhat on the same level. except migo is the jackpot and the blank body is whiff.
 	return ..()
 
-/datum/micro_organism/cell_line/clown/fuck_up_growing(obj/machinery/vatgrower/vat)
-	vat.visible_message(span_warning("The biological sample in [vat] seems to have created something horrific!"))
+/datum/micro_organism/cell_line/clown
 
-	var/mob/selected_mob = pick(list(/mob/living/basic/clown/mutant, /mob/living/basic/clown/fleshclown))
+/datum/micro_organism/cell_line/clown/succeed_growing(obj/machinery/vatgrower/vat)
+	if(vat.reagents.has_reagent(/datum/reagent/toxin/mutagen) && prob(CYTO_SHINY_CHANCE))
+		resulting_atom = pick(/mob/living/basic/clown/mutant, /mob/living/basic/clown/fleshclown)
+		vat.visible_message(span_warning("The biological sample in [vat] mutates into something horrific!"))
+	else
+		resulting_atom = initial(resulting_atom)
+	return ..()
 
-	new selected_mob(get_turf(vat))
+/datum/micro_organism/cell_line/clown/New()
+	. = ..()
+	// all clown mutations get a huge boost from mutagen, at the cost of causing occasional mutations
+	supplementary_reagents[/datum/reagent/toxin/mutagen] = 8
 
 /datum/micro_organism/cell_line/clown/bananaclown
 	desc = "Clown bits with banana chunks"
@@ -655,11 +664,15 @@
 	virus_suspectibility = 0
 	resulting_atom = /obj/item/queen_bee/bought
 
-/datum/micro_organism/cell_line/queen_bee/fuck_up_growing(obj/machinery/vatgrower/vat) //we love job hazards
-	vat.visible_message(span_warning("You hear angry buzzing coming from the inside of the vat!"))
-	for(var/i in 1 to 5)
-		new /mob/living/basic/bee(get_turf(vat))
-
+/datum/micro_organism/cell_line/queen_bee/succeed_growing(obj/machinery/vatgrower/vat)
+	if(grow_count % 2) // every other growth cycle spawns a horde of bees insteads
+		resulting_atom_count = 5
+		resulting_atom = /mob/living/basic/bee
+		vat.visible_message(span_warning("You hear angry buzzing coming from the inside of the vat!"))
+	else
+		resulting_atom_count = initial(resulting_atom_count)
+		resulting_atom = initial(resulting_atom)
+	return ..()
 
 /datum/micro_organism/cell_line/butterfly
 	desc = "Papilionoidea cells"