diff --git a/code/modules/atmospherics/machinery/components/unary_devices/cryo.dm b/code/modules/atmospherics/machinery/components/unary_devices/cryo.dm
index f90f84a95aa..cda455d2781 100644
--- a/code/modules/atmospherics/machinery/components/unary_devices/cryo.dm
+++ b/code/modules/atmospherics/machinery/components/unary_devices/cryo.dm
@@ -186,7 +186,7 @@
 			mob_occupant.Unconscious((mob_occupant.bodytemperature * unconscious_factor) * 2000)
 		if(beaker)
 			if(reagent_transfer == 0) // Magically transfer reagents. Because cryo magic.
-				beaker.reagents.trans_to(occupant, 1, 10 * efficiency) // Transfer reagents, multiplied because cryo magic.
+				beaker.reagents.trans_to(occupant, 1, efficiency * 0.25) // Transfer reagents.
 				beaker.reagents.reaction(occupant, VAPOR)
 				air1.gases[/datum/gas/oxygen][MOLES] -= 2 / efficiency //Let's use gas for this
 			if(++reagent_transfer >= 10 * efficiency) // Throttle reagent transfer (higher efficiency will transfer the same amount but consume less from the beaker).
diff --git a/code/modules/reagents/chemistry/reagents/medicine_reagents.dm b/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
index 095db17c7f7..d80a8b3e58a 100644
--- a/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
+++ b/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
@@ -128,31 +128,16 @@
 	taste_description = "sludge"
 
 /datum/reagent/medicine/cryoxadone/on_mob_life(mob/living/M)
-	switch(M.bodytemperature) // Low temperatures are required to take effect.
-		if(0 to 100) // At extreme temperatures (upgraded cryo) the effect is greatly increased.
-			M.status_flags &= ~DISFIGURED
-			M.adjustCloneLoss(-1, 0)
-			M.adjustOxyLoss(-9, 0)
-			M.adjustBruteLoss(-5, 0)
-			M.adjustFireLoss(-5, 0)
-			M.adjustToxLoss(-5, 0)
-			. = 1
-		if(100 to 225) // At lower temperatures (cryo) the full effect is boosted
-			M.status_flags &= ~DISFIGURED
-			M.adjustCloneLoss(-1, 0)
-			M.adjustOxyLoss(-7, 0)
-			M.adjustBruteLoss(-3, 0)
-			M.adjustFireLoss(-3, 0)
-			M.adjustToxLoss(-3, 0)
-			. = 1
-		if(225 to T0C)
-			M.status_flags &= ~DISFIGURED
-			M.adjustCloneLoss(-1, 0)
-			M.adjustOxyLoss(-5, 0)
-			M.adjustBruteLoss(-1, 0)
-			M.adjustFireLoss(-1, 0)
-			M.adjustToxLoss(-1, 0)
-			. = 1
+	var/power = -0.00003 * (M.bodytemperature ** 2) + 3
+	if(M.bodytemperature < T0C)
+		M.adjustOxyLoss(-3 * power, 0)
+		M.adjustBruteLoss(-power, 0)
+		M.adjustFireLoss(-power, 0)
+		M.adjustToxLoss(-power, 0)
+		M.adjustCloneLoss(-power, 0)
+		M.status_flags &= ~DISFIGURED
+		. = 1
+	metabolization_rate = REAGENTS_METABOLISM * (0.00001 * (M.bodytemperature ** 2) + 0.5)
 	..()
 
 /datum/reagent/medicine/clonexadone
@@ -164,19 +149,11 @@
 	metabolization_rate = 1.5 * REAGENTS_METABOLISM
 
 /datum/reagent/medicine/clonexadone/on_mob_life(mob/living/M)
-	switch(M.bodytemperature) // Low temperatures are required to take effect.
-		if(0 to 100) // At extreme temperatures (upgraded cryo) the effect is greatly increased.
-			M.status_flags &= ~DISFIGURED
-			M.adjustCloneLoss(-7, 0)
-			. = 1
-		if(100 to 225) // At lower temperatures (cryo) the full effect is boosted
-			M.status_flags &= ~DISFIGURED
-			M.adjustCloneLoss(-3, 0)
-			. = 1
-		if(225 to T0C)
-			M.status_flags &= ~DISFIGURED
-			M.adjustCloneLoss(-2, 0)
-			. = 1
+	if(M.bodytemperature < T0C)
+		M.adjustCloneLoss(0,00006 * (M.bodytemperature ** 2) - 6, 0)
+		M.status_flags &= ~DISFIGURED
+		. = 1
+	metabolization_rate = REAGENTS_METABOLISM * (0.000015 * (M.bodytemperature ** 2) + 0.75)
 	..()
 
 /datum/reagent/medicine/rezadone