diff --git a/code/modules/plumbing/plumbers/plumbing_buffer.dm b/code/modules/plumbing/plumbers/plumbing_buffer.dm
index b2bb21bc24e..7b3ef306d04 100644
--- a/code/modules/plumbing/plumbers/plumbing_buffer.dm
+++ b/code/modules/plumbing/plumbers/plumbing_buffer.dm
@@ -33,11 +33,11 @@
 	SIGNAL_HANDLER
 	if(!buffer_net)
 		return
-	if(reagents.total_volume + CHEMICAL_QUANTISATION_LEVEL >= activation_volume && mode == UNREADY)
+	if(reagents.total_volume >= activation_volume && mode == UNREADY)
 		mode = IDLE
 		buffer_net.check_active()
 
-	else if(reagents.total_volume + CHEMICAL_QUANTISATION_LEVEL < activation_volume && mode != UNREADY)
+	else if(reagents.total_volume < activation_volume && mode != UNREADY)
 		mode = UNREADY
 		buffer_net.check_active()
 
diff --git a/code/modules/plumbing/plumbers/reaction_chamber.dm b/code/modules/plumbing/plumbers/reaction_chamber.dm
index 965b428acbd..2b56bfb4ae6 100644
--- a/code/modules/plumbing/plumbers/reaction_chamber.dm
+++ b/code/modules/plumbing/plumbers/reaction_chamber.dm
@@ -43,7 +43,7 @@
 /obj/machinery/plumbing/reaction_chamber/proc/on_reagent_change(datum/reagents/holder, ...)
 	SIGNAL_HANDLER
 
-	if(holder.total_volume <= CHEMICAL_VOLUME_ROUNDING && emptying) //we were emptying, but now we aren't
+	if(!holder.total_volume && emptying) //we were emptying, but now we aren't
 		emptying = FALSE
 		holder.flags |= NO_REACT
 	return NONE
diff --git a/code/modules/reagents/chemistry/holder/holder.dm b/code/modules/reagents/chemistry/holder/holder.dm
index 112c9fca8a1..867245e9c25 100644
--- a/code/modules/reagents/chemistry/holder/holder.dm
+++ b/code/modules/reagents/chemistry/holder/holder.dm
@@ -129,7 +129,6 @@
 		amount = adjusted_vol
 		has_split = TRUE
 
-	update_total()
 	var/cached_total = total_volume
 	if(cached_total + amount > maximum_volume)
 		amount = maximum_volume - cached_total //Doesnt fit in. Make it disappear. shouldn't happen. Will happen.
@@ -195,7 +194,7 @@
 			set_temperature(reagtemp)
 
 	SEND_SIGNAL(src, COMSIG_REAGENTS_NEW_REAGENT, new_reagent, amount, reagtemp, data, no_react)
-	if(!no_react)
+	if(!no_react && !is_reacting)
 		handle_reactions()
 	return amount
 
diff --git a/code/modules/reagents/chemistry/holder/reactions.dm b/code/modules/reagents/chemistry/holder/reactions.dm
index 30148802e08..d7f959abbb1 100644
--- a/code/modules/reagents/chemistry/holder/reactions.dm
+++ b/code/modules/reagents/chemistry/holder/reactions.dm
@@ -190,7 +190,6 @@
 	if(!LAZYLEN(reaction_list))
 		finish_reacting()
 	else
-		update_total()
 		handle_reactions()
 
 /*
diff --git a/code/modules/reagents/chemistry/recipes.dm b/code/modules/reagents/chemistry/recipes.dm
index 579dcb52370..26fb0f472dd 100644
--- a/code/modules/reagents/chemistry/recipes.dm
+++ b/code/modules/reagents/chemistry/recipes.dm
@@ -182,7 +182,8 @@
 		var/datum/reagent/reagent = holder.has_reagent(id)
 		if(!reagent)
 			return
-		reagent.volume = round((reagent.volume * 0.98), CHEMICAL_QUANTISATION_LEVEL) //Slowly lower yield per tick
+		reagent.volume *= 0.98 //Slowly lower yield per tick
+	holder.update_total()
 
 /**
  * Occurs when a reation is too impure (i.e. it's below purity_min)
diff --git a/code/modules/reagents/chemistry/recipes/pyrotechnics.dm b/code/modules/reagents/chemistry/recipes/pyrotechnics.dm
index f1fb70faf38..78942431bb8 100644
--- a/code/modules/reagents/chemistry/recipes/pyrotechnics.dm
+++ b/code/modules/reagents/chemistry/recipes/pyrotechnics.dm
@@ -15,7 +15,7 @@
 
 /datum/chemical_reaction/reagent_explosion/nitroglycerin/on_reaction(datum/reagents/holder, datum/equilibrium/reaction, created_volume)
 
-	if(holder.has_reagent(/datum/reagent/exotic_stabilizer,round(created_volume / 25, CHEMICAL_QUANTISATION_LEVEL)))
+	if(holder.has_reagent(/datum/reagent/exotic_stabilizer, created_volume / 25))
 		return
 	holder.remove_reagent(/datum/reagent/nitroglycerin, created_volume * 2)
 	..()
@@ -78,10 +78,10 @@
 	strengthdiv = 3
 
 /datum/chemical_reaction/reagent_explosion/tatp/update_info()
-	required_temp = 450 + rand(-49,49)  //this gets loaded only on round start
+	required_temp = 450 + rand(-49, 49)  //this gets loaded only on round start
 
 /datum/chemical_reaction/reagent_explosion/tatp/on_reaction(datum/reagents/holder, datum/equilibrium/reaction, created_volume)
-	if(holder.has_reagent(/datum/reagent/exotic_stabilizer,round(created_volume / 50, CHEMICAL_QUANTISATION_LEVEL))) // we like exotic stabilizer
+	if(holder.has_reagent(/datum/reagent/exotic_stabilizer, created_volume / 50)) // we like exotic stabilizer
 		return
 	holder.remove_reagent(/datum/reagent/tatp, created_volume)
 	..()
diff --git a/code/modules/surgery/organs/internal/liver/_liver.dm b/code/modules/surgery/organs/internal/liver/_liver.dm
index 92e2cb0039f..33dcaa83fd1 100755
--- a/code/modules/surgery/organs/internal/liver/_liver.dm
+++ b/code/modules/surgery/organs/internal/liver/_liver.dm
@@ -142,7 +142,7 @@
 		for(var/datum/reagent/toxin/toxin in cached_reagents)
 			if(toxin.affected_organ_flags && !(organ_flags & toxin.affected_organ_flags)) //this particular toxin does not affect this type of organ
 				continue
-			var/amount = round(toxin.volume, CHEMICAL_QUANTISATION_LEVEL) // this is an optimization
+			var/amount = toxin.volume
 			if(belly)
 				amount += belly.reagents.get_reagent_amount(toxin.type)