diff --git a/code/__defines/chemistry.dm b/code/__defines/chemistry.dm
index 08131f99bb..3ae84811b5 100644
--- a/code/__defines/chemistry.dm
+++ b/code/__defines/chemistry.dm
@@ -36,6 +36,10 @@
 
 #define REAGENTS_PER_SHEET 20
 
+#define ANTIBIO_NORM	1
+#define ANTIBIO_OD		2
+#define ANTIBIO_SUPER	3
+
 // Chemistry lists.
 var/list/tachycardics  = list("coffee", "inaprovaline", "hyperzine", "nitroglycerin", "thirteenloko", "nicotine") // Increase heart rate.
 var/list/bradycardics  = list("neurotoxin", "cryoxadone", "clonexadone", "space_drugs", "stoxin")                 // Decrease heart rate.
diff --git a/code/modules/organs/organ.dm b/code/modules/organs/organ.dm
index 93565ac72d..16cb6db64e 100644
--- a/code/modules/organs/organ.dm
+++ b/code/modules/organs/organ.dm
@@ -148,25 +148,25 @@ var/list/organ_cache = list()
 		germ_level = 0
 		return 0
 
-	var/antibiotics = owner.reagents.get_reagent_amount("spaceacillin")
+	var/antibiotics = owner.chem_effects[CE_ANTIBIOTIC] || 0
 
 	var/infection_damage = 0
 
-	if((status & ORGAN_DEAD) && antibiotics < 30) //Sepsis from 'dead' organs
+	if((status & ORGAN_DEAD) && antibiotics < ANTIBIO_OD) //Sepsis from 'dead' organs
 		infection_damage = min(1, 1 + round((germ_level - INFECTION_LEVEL_THREE)/200,0.25)) //1 Tox plus a little based on germ level
 
-	else if(germ_level > INFECTION_LEVEL_TWO && antibiotics < 30)
+	else if(germ_level > INFECTION_LEVEL_TWO && antibiotics < ANTIBIO_OD)
 		infection_damage = min(0.25, 0.25 + round((germ_level - INFECTION_LEVEL_TWO)/200,0.25))
 
 	if(infection_damage)
 		owner.adjustToxLoss(infection_damage)
 
 	if (germ_level > 0 && germ_level < INFECTION_LEVEL_ONE/2 && prob(30))
-		adjust_germ_level(-1)
+		adjust_germ_level(-antibiotics)
 
 	if (germ_level >= INFECTION_LEVEL_ONE/2)
 		//aiming for germ level to go from ambient to INFECTION_LEVEL_TWO in an average of 15 minutes
-		if(antibiotics < 5 && prob(round(germ_level/6)))
+		if(!antibiotics && prob(round(germ_level/6)))
 			adjust_germ_level(1)
 
 	if(germ_level >= INFECTION_LEVEL_ONE)
@@ -181,7 +181,7 @@ var/list/organ_cache = list()
 		. = 2 //Organ qualifies for effect-specific processing
 		//No particular effect on the general 'organ' at 3
 
-	if (germ_level >= INFECTION_LEVEL_THREE && antibiotics < 30)
+	if (germ_level >= INFECTION_LEVEL_THREE && antibiotics < ANTIBIO_OD)
 		. = 3 //Organ qualifies for effect-specific processing
 		adjust_germ_level(rand(5,10)) //Germ_level increases without overdose of antibiotics
 
@@ -234,19 +234,19 @@ var/list/organ_cache = list()
 
 //Germs
 /obj/item/organ/proc/handle_antibiotics()
-	var/antibiotics = owner.reagents.get_reagent_amount("spaceacillin")
+	var/antibiotics = owner.chem_effects[CE_ANTIBIOTIC] || 0
 
-	if (!germ_level || antibiotics < 5)
+	if (!germ_level || antibiotics < ANTIBIO_NORM)
 		return
 
 	if (germ_level < INFECTION_LEVEL_ONE)
 		germ_level = 0	//cure instantly
 	else if (germ_level < INFECTION_LEVEL_TWO)
-		adjust_germ_level(-6)	//at germ_level < 500, this should cure the infection in a minute
+		adjust_germ_level(-antibiotics*4)	//at germ_level < 500, this should cure the infection in a minute
 	else if (germ_level < INFECTION_LEVEL_THREE)
-		adjust_germ_level(-2) //at germ_level < 1000, this will cure the infection in 5 minutes
+		adjust_germ_level(-antibiotics*2) //at germ_level < 1000, this will cure the infection in 5 minutes
 	else
-		adjust_germ_level(-1)	// You waited this long to get treated, you don't really deserve this organ
+		adjust_germ_level(-antibiotics)	// You waited this long to get treated, you don't really deserve this organ
 
 //Adds autopsy data for used_weapon.
 /obj/item/organ/proc/add_autopsy_data(var/used_weapon, var/damage)
diff --git a/code/modules/reagents/Chemistry-Reagents.dm b/code/modules/reagents/Chemistry-Reagents.dm
index fe480ed574..ddfa5823e5 100644
--- a/code/modules/reagents/Chemistry-Reagents.dm
+++ b/code/modules/reagents/Chemistry-Reagents.dm
@@ -101,7 +101,7 @@
 /datum/reagent/proc/affect_touch(var/mob/living/carbon/M, var/alien, var/removed)
 	return
 
-/datum/reagent/proc/overdose(var/mob/living/carbon/M, var/alien, var/removed) // Overdose effect. Doesn't happen instantly.
+/datum/reagent/proc/overdose(var/mob/living/carbon/M, var/alien, var/removed) // Overdose effect.
 	if(alien == IS_DIONA)
 		return
 	if(ishuman(M))
diff --git a/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm b/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm
index b731f50326..4818dc808f 100644
--- a/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm
+++ b/code/modules/reagents/Chemistry-Reagents/Chemistry-Reagents-Medicine.dm
@@ -509,11 +509,46 @@
 	taste_description = "bitterness"
 	reagent_state = LIQUID
 	color = "#C1C1C1"
-	metabolism = REM * 0.05
+	metabolism = REM * 0.25
 	mrate_static = TRUE
 	overdose = REAGENTS_OVERDOSE
 	scannable = 1
 
+/datum/reagent/spaceacillin/affect_blood(var/mob/living/carbon/M, var/alien, var/removed)
+	..()
+	M.add_chemical_effect(CE_ANTIBIOTIC, dose >= overdose ? ANTIBIO_OD : ANTIBIO_NORM)
+
+/datum/reagent/corophizine
+	name = "Corophizine"
+	id = "corophizine"
+	description = "A wide-spectrum antibiotic drug. Powerful and uncomfortable in equal doses."
+	taste_description = "burnt toast"
+	reagent_state = LIQUID
+	color = "#FFB0B0"
+	mrate_static = TRUE
+	overdose = 10
+	scannable = 1
+
+/datum/reagent/corophizine/affect_blood(var/mob/living/carbon/M, var/alien, var/removed)
+	..()
+	M.add_chemical_effect(CE_ANTIBIOTIC, ANTIBIO_SUPER)
+	
+	//Based roughly on Levofloxacin's rather severe side-effects
+	if(prob(20))
+		M.Confuse(5)
+	if(prob(20))
+		M.Weaken(5)
+	if(prob(20))
+		M.make_dizzy(5)
+	if(prob(20))
+		M.hallucination = max(M.hallucination, 10)
+	
+	//One of the levofloxacin side effects is 'spontaneous tendon rupture', which I'll immitate here. 1:1000 chance, so, pretty darn rare.
+	if(ishuman(M) && rand(1,1000) == 1)
+		var/mob/living/carbon/human/H = M
+		var/obj/item/organ/external/eo = pick(H.organs) //Misleading variable name, 'organs' is only external organs
+		eo.fracture()
+
 /datum/reagent/sterilizine
 	name = "Sterilizine"
 	id = "sterilizine"
diff --git a/code/modules/reagents/Chemistry-Recipes.dm b/code/modules/reagents/Chemistry-Recipes.dm
index 3df633c45b..0feae58505 100644
--- a/code/modules/reagents/Chemistry-Recipes.dm
+++ b/code/modules/reagents/Chemistry-Recipes.dm
@@ -417,6 +417,14 @@
 	required_reagents = list("cryptobiolin" = 1, "inaprovaline" = 1)
 	result_amount = 2
 
+/datum/chemical_reaction/corophizine
+	name = "Corophizine"
+	id = "corophizine"
+	result = "corophizine"
+	required_reagents = list("spaceacillin" = 1, "carbon" = 1, "phoron" = 0.1)
+	catalysts = list("phoron" = 5)
+	result_amount = 2
+
 /datum/chemical_reaction/imidazoline
 	name = "imidazoline"
 	id = "imidazoline"