diff --git a/code/datums/diseases/advance/advance.dm b/code/datums/diseases/advance/advance.dm
index 6a41b710..ed0cc337 100644
--- a/code/datums/diseases/advance/advance.dm
+++ b/code/datums/diseases/advance/advance.dm
@@ -354,10 +354,12 @@
 	else
 		RemoveSymptom(pick(symptoms))
 		symptoms += S
+		S.OnAdd(src)
 
 // Simply removes the symptom.
 /datum/disease/advance/proc/RemoveSymptom(datum/symptom/S)
 	symptoms -= S
+	S.OnRemove(src)
 
 // Neuter a symptom, so it will only affect stats
 /datum/disease/advance/proc/NeuterSymptom(datum/symptom/S)