diff --git a/code/modules/reagents/Chemistry-Reagents-Antidepressants.dm b/code/modules/reagents/Chemistry-Reagents-Antidepressants.dm
index af38b559489..392d9101c6d 100644
--- a/code/modules/reagents/Chemistry-Reagents-Antidepressants.dm
+++ b/code/modules/reagents/Chemistry-Reagents-Antidepressants.dm
@@ -68,11 +68,18 @@
 		else
 			if(world.time > data + ANTIDEPRESSANT_MESSAGE_DELAY)
 				data = world.time
-				if(prob(90))
-					M << "\blue Your mind feels much more stable."
+				if(volume > 5)						// Bone White - Added any concentrations over 5 units to cause higher chance of mind breakage.
+					if (prob(min(100, volume * 5)))
+						M << "\red Your mind breaks apart.."
+						M.hallucination += 200
+					else
+						M << "\blue Your mind feels much more stable."
 				else
-					M << "\red Your mind breaks apart.."
-					M.hallucination += 200
+					if (prob(90))
+						M << "\blue Your mind feels much more stable."
+					else
+						M << "\red Your mind breaks apart.."
+						M.hallucination += 200
 		..()
 		return
 
diff --git a/code/modules/reagents/Chemistry-Reagents.dm b/code/modules/reagents/Chemistry-Reagents.dm
index 34dda1f2064..a52bf3f4054 100644
--- a/code/modules/reagents/Chemistry-Reagents.dm
+++ b/code/modules/reagents/Chemistry-Reagents.dm
@@ -108,13 +108,13 @@ datum
 
 					if( (toxod > 0) && (volume >= toxod))//Toxin Overdosing
 						M.adjustToxLoss(overdose_dam * volume / toxod)
-						
+
 					if(	(bruteod > 0) && (volume >= bruteod))//Brute Overdosing
 						M.take_overall_damage(overdose_dam * volume / bruteod, 0)
-						
+
 					if( (burnod > 0) && (volume >= burnod))//Burn Overdosing
 						M.take_overall_damage(0, overdose_dam * volume / burnod)
-						
+
 					if( (oxyod > 0) && (volume >= oxyod))//Oxygen Overdosing
 						M.adjustOxyLoss(overdose_dam * volume / oxyod)
 
@@ -363,7 +363,7 @@ datum
 			color = "#006400" // rgb: 0, 100, 0
 			bruteod = BRUTE_OVERDOSE
 			burnod = BURN_OVERDOSE
-
+			mildly_toxic = 0
 			on_mob_life(var/mob/living/M as mob)
 				if(!M) M = holder.my_atom
 				if(holder.has_reagent("toxin"))
@@ -526,8 +526,8 @@ datum
 			description = "An effective hypnotic used to treat insomnia."
 			reagent_state = LIQUID
 			color = "#E895CC" // rgb: 232, 149, 204
-			toxod = TOX_OVERDOSE
-			oxyod = OXY_OVERDOSE
+			toxod = 40
+			oxyod = 40
 
 			on_mob_life(var/mob/living/M as mob)
 				if(!M) M = holder.my_atom
@@ -550,7 +550,7 @@ datum
 			description = "Put people to sleep, and heals them."
 			reagent_state = LIQUID
 			color = "#C8A5DC" // rgb: 200, 165, 220
-
+			mildly_toxic = 0
 			on_mob_life(var/mob/living/M as mob)
 				if(!M) M = holder.my_atom
 				if(!data) data = 1
@@ -583,8 +583,8 @@ datum
 			description = "Inaprovaline is a synaptic stimulant and cardiostimulant. Commonly used to stabilize patients."
 			reagent_state = LIQUID
 			color = "#C8A5DC" // rgb: 200, 165, 220
-			bruteod = BRUTE_OVERDOSE
-			oxyod = OXY_OVERDOSE
+			bruteod = 40
+			oxyod = 40
 			scannable = 1
 
 			on_mob_life(var/mob/living/M as mob, var/alien)
@@ -723,7 +723,7 @@ datum
 			id = "oxygen"
 			description = "A colorless, odorless gas."
 			reagent_state = GAS
-			color = "#808080" // rgb: 128, 128, 128			
+			color = "#808080" // rgb: 128, 128, 128
 
 			custom_metabolism = 0.01
 
@@ -1636,8 +1636,10 @@ datum
 			description = "Dexalin is used in the treatment of oxygen deprivation."
 			reagent_state = LIQUID
 			color = "#C8A5DC" // rgb: 200, 165, 220
-			toxod = TOX_OVERDOSE
-			burnod = BURN_OVERDOSE
+			toxod = 40
+			burnod = 40
+			bruteod = 40
+			oxyod = 40
 			scannable = 1
 
 			on_mob_life(var/mob/living/M as mob, var/alien)
diff --git a/code/modules/virus2/effect.dm b/code/modules/virus2/effect.dm
index 456b7ecc819..f73b325190f 100644
--- a/code/modules/virus2/effect.dm
+++ b/code/modules/virus2/effect.dm
@@ -200,6 +200,13 @@
 
 ////////////////////////STAGE 4/////////////////////////////////
 
+/datum/disease2/effect/alchdranine
+	name = "Panacea Effect"
+	stage = 4
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.reagents.get_reagent_amount("alchdranine") < 1)
+			mob.reagents.add_reagent("alchdranine", 1)
+
 /datum/disease2/effect/viralsputum_major
 	name = "Hemoptysis"
 	stage = 4
@@ -210,7 +217,7 @@
 			if(D==null)
 				D = new(get_turf(mob))
 			D.virus2 |= virus_copylist(mob.virus2)
-			mob.reagents.remove_reagent("blood", 50) // Bone White - Blood loss when coughing up blood, experimental, may need adjusting.
+			mob.reagents.remove_reagent("blood", 20) // Bone White - Blood loss when coughing up blood, experimental, may need adjusting.
 		else
 
 /datum/disease2/effect/gibbingtons
@@ -507,6 +514,28 @@
 
 ////////////////////////STAGE 3/////////////////////////////////
 
+/datum/disease2/effect/brain_regen
+	name = "Regenerative Synapse Effect"
+	stage = 3
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.reagents.get_reagent_amount("alkysine") < 1)
+			mob.reagents.add_reagent("alkysine", 1)
+
+/datum/disease2/effect/paroxetine
+	name = "Psyche Collapse Syndrome"
+	stage = 3
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.reagents.get_reagent_amount("paroxetine") < 10)
+			mob.reagents.add_reagent("paroxetine", 1)
+
+/datum/disease2/effect/pain_major
+	name = "Phantom Pain Syndrome"
+	stage = 3
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.halloss < 100)
+			mob << "<span class = 'warning'> You feel like your body is on fire. Make the pain stop!</span>"
+			mob.apply_effect(20,AGONY,0)
+
 // === burn brute toxin clone brain damage symptoms - Bone White ===
 
 /datum/disease2/effect/burn
@@ -779,15 +808,23 @@ var/list/compatible_mobs = list(/mob/living/carbon/human, /mob/living/carbon/mon
 */
 
 
-/datum/disease2/effect/paroxetine
-	name = "Psyche Collapse Syndrome"
-	stage = 3
-	activate(var/mob/living/carbon/mob,var/multiplier)
-		if (mob.reagents.get_reagent_amount("paroxetine") < 5)
-			mob.reagents.add_reagent("paroxetine", 1)
-
 ////////////////////////STAGE 2/////////////////////////////////
 
+/datum/disease2/effect/methylphenidate
+	name = "Mental Stability Phenomenon"
+	stage = 2
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.reagents.get_reagent_amount("methylphenidate") < 5)
+			mob.reagents.add_reagent("methylphenidate", 1)
+
+/datum/disease2/effect/pain
+	name = "Acute Muscle Ache"
+	stage = 2
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.halloss < 50)
+			mob << "<span class='warning'>You ache all over!</span>"
+			mob.apply_effect(10,AGONY,0)
+
 // === burn brute toxin clone brain damage symptoms - Bone White ===
 
 /datum/disease2/effect/burn
@@ -885,14 +922,14 @@ var/list/compatible_mobs = list(/mob/living/carbon/human, /mob/living/carbon/mon
 					H.h_style = "Balding Hair"
 					H.update_hair()
 
-/datum/disease2/effect/stimulant
-	name = "Adrenaline Extra"
+/datum/disease2/effect/stimulant_major
+	name = "Adrenal Overload"
 	stage = 2
 	activate(var/mob/living/carbon/mob,var/multiplier)
-		mob << "<span class='notice'>You feel a rush of energy inside you!</span>"
-		if (mob.reagents.get_reagent_amount("hyperzine") < 10)
+		if (mob.reagents.get_reagent_amount("hyperzine") < 40)
 			mob.reagents.add_reagent("hyperzine", 4)
 		if (prob(30))
+			mob << "<span class='notice'>You feel a rush of energy inside you!</span>"
 			mob.jitteriness += 10
 
 /datum/disease2/effect/drunk
@@ -950,7 +987,7 @@ var/list/compatible_mobs = list(/mob/living/carbon/human, /mob/living/carbon/mon
 			if(D==null)
 				D = new(get_turf(mob))
 			D.virus2 |= virus_copylist(mob.virus2)
-			mob.reagents.remove_reagent("blood", 20) // Bone White - Blood loss when coughing up blood, experimental, may need adjusting.
+			mob.reagents.remove_reagent("blood", 5) // Bone White - Blood loss when coughing up blood, experimental, may need adjusting.
 
 
 /datum/disease2/effect/lantern
@@ -972,7 +1009,30 @@ var/list/compatible_mobs = list(/mob/living/carbon/human, /mob/living/carbon/mon
 
 ////////////////////////STAGE 1/////////////////////////////////
 
+/datum/disease2/effect/citalopram
+	name = "Reality Check"
+	stage = 1
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.reagents.get_reagent_amount("citalopram") < 5)
+			mob.reagents.add_reagent("citalopram", 1)
 
+/datum/disease2/effect/pain_minor
+	name = "Heightened Sensitivity"
+	stage = 1
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.halloss < 20)
+			mob << "<span class='warning'>Your body aches.</span>"
+			mob.apply_effect(5,AGONY,0)
+
+/datum/disease2/effect/stimulant
+	name = "Adrenaline Extra"
+	stage = 1
+	activate(var/mob/living/carbon/mob,var/multiplier)
+		if (mob.reagents.get_reagent_amount("hyperzine") < 10)
+			mob.reagents.add_reagent("hyperzine", 4)
+		if (prob(30))
+			mob << "<span class='notice'>You feel a rush of energy inside you!</span>"
+			mob.jitteriness += 10
 
 /datum/disease2/effect/cough_minor
 	name = "Trachea Sensitivity"