diff --git a/baystation12.dme b/baystation12.dme
index 23869be99c5..5c1545fc992 100644
--- a/baystation12.dme
+++ b/baystation12.dme
@@ -1429,6 +1429,7 @@
 #include "code\WorkInProgress\Cael_Aislinn\Supermatter\SuperMatter.dm"
 #include "code\WorkInProgress\Cael_Aislinn\Supermatter\ZeroPointLaser.dm"
 #include "code\WorkInProgress\Chinsky\ashtray.dm"
+#include "code\WorkInProgress\Cib\MedicalSideEffects.dm"
 #include "code\WorkInProgress\Mini\ATM.dm"
 #include "code\WorkInProgress\Ported\policetape.dm"
 #include "code\WorkInProgress\SkyMarshal\Ultralight_procs.dm"
diff --git a/code/WorkInProgress/Cib/MedicalSideEffects.dm b/code/WorkInProgress/Cib/MedicalSideEffects.dm
new file mode 100644
index 00000000000..eb23d21b141
--- /dev/null
+++ b/code/WorkInProgress/Cib/MedicalSideEffects.dm
@@ -0,0 +1,63 @@
+// MEDICAL SIDE EFFECT BASE
+// ========================
+/datum/medical_effect/var/name = "None"
+/datum/medical_effect/var/strength = 0
+/datum/medical_effect/proc/on_life(mob/living/carbon/human/H, strength)
+/datum/medical_effect/proc/cure(mob/living/carbon/human/H)
+
+
+// MOB HELPERS
+// ===========
+/mob/living/carbon/human/var/list/datum/medical_effect/side_effects = list()
+/mob/proc/add_side_effect(name, strength = 0)
+/mob/living/carbon/human/add_side_effect(name, strength = 0)
+	for(var/datum/medical_effect/M in src.side_effects) if(M.name == name)
+		M.strength = max(M.strength, strength = 10)
+		return
+
+	var/list/L = typesof(/datum/medical_effect)-/datum/medical_effect
+
+	for(var/T in L)
+		var/datum/medical_effect/M = new T
+		if(M.name == name)
+			M.strength = strength
+			side_effects += M
+
+/mob/living/carbon/human/proc/handle_medical_side_effects()
+	// One full cycle(in terms of strength) every 10 minutes
+	var/strength_percent = sin(life_tick / 300)
+
+	// Only do anything if the effect is currently strong enough
+	if(strength_percent >= 0.4)
+		for (var/datum/medical_effect/M in side_effects)
+			if (M.cure())
+				side_effects -= M
+				del(M)
+			else
+				if(life_tick % 30 == 0)
+					M.on_life(src, strength_percent*M.strength)
+				// Effect slowly growing stronger
+				M.strength+=0.2
+
+// HEADACHE
+// ========
+/datum/medical_effect/headache/name = "Headache"
+/datum/medical_effect/headache/on_life(mob/living/carbon/human/H, strength)
+	switch(strength)
+		if(1 to 10)
+			H.custom_pain("You feel a light pain in your head.",0)
+		if(11 to 30)
+			H.custom_pain("You feel a throbbing pain in your head!",1)
+		if(31 to 99)
+			H.custom_pain("You feel an excrutiating pain in your head!",1)
+			H.adjustBrainLoss(1)
+		if(99 to INFINITY)
+			H.custom_pain("It feels like your head is about to split open!",1)
+			H.adjustBrainLoss(3)
+			var/datum/organ/external/O = H.organs_by_name["head"]
+			O.take_damage(0, 1, 0, "Headache")
+
+/datum/medical_effect/headache/cure(mob/living/carbon/human/H)
+	if(H.reagents.has_reagent("alkysine"))
+		return 1
+	return 0
\ No newline at end of file
diff --git a/code/modules/client/preferences_savefile.dm b/code/modules/client/preferences_savefile.dm
index 80d5e718df0..5727e7b671e 100644
--- a/code/modules/client/preferences_savefile.dm
+++ b/code/modules/client/preferences_savefile.dm
@@ -143,6 +143,8 @@
 	S["skills"]				>> skills
 	S["skill_specialization"] >> skill_specialization
 	S["organ_data"]			>> organ_data
+
+	S["nanotrasen_relation"] >> nanotrasen_relation
 	//S["skin_style"]			>> skin_style
 
 	//Sanitize
@@ -238,6 +240,8 @@
 	S["skills"]				<< skills
 	S["skill_specialization"] << skill_specialization
 	S["organ_data"]			<< organ_data
+
+	S["nanotrasen_relation"] << nanotrasen_relation
 	//S["skin_style"]			<< skin_style
 
 	return 1
diff --git a/code/modules/mob/living/carbon/human/life.dm b/code/modules/mob/living/carbon/human/life.dm
index d0cb78eba13..9f69aa85583 100644
--- a/code/modules/mob/living/carbon/human/life.dm
+++ b/code/modules/mob/living/carbon/human/life.dm
@@ -99,6 +99,8 @@ var/const/BLOOD_VOLUME_SURVIVE = 122
 
 	handle_pain()
 
+	handle_medical_side_effects()
+
 	//Status updates, death etc.
 	handle_regular_status_updates()		//TODO: optimise ~Carn
 	update_canmove()
diff --git a/code/modules/reagents/Chemistry-Reagents.dm b/code/modules/reagents/Chemistry-Reagents.dm
index acec96cba7c..623e45c6cd1 100644
--- a/code/modules/reagents/Chemistry-Reagents.dm
+++ b/code/modules/reagents/Chemistry-Reagents.dm
@@ -1501,6 +1501,7 @@ datum
 					return
 				if(!M) M = holder.my_atom
 				M.heal_organ_damage(2*REM,0)
+				M.add_side_effect("Headache")
 				..()
 				return