diff --git a/code/__HELPERS/trait_helpers.dm b/code/__HELPERS/trait_helpers.dm
index 5c4592a3141..85eff70a89a 100644
--- a/code/__HELPERS/trait_helpers.dm
+++ b/code/__HELPERS/trait_helpers.dm
@@ -182,6 +182,7 @@ Remember to update _globalvars/traits.dm if you're adding/removing/renaming trai
 #define TRAIT_FLASH_PROTECTION	"flash_protection"
 #define TRAIT_NIGHT_VISION		"night_vision"
 #define TRAIT_EMOTE_MUTE		"emote_mute"
+#define TRAIT_HYPOSPRAY_IMMUNE	"hypospray_immune" // For making crew-accessable hyposprays not pierce your clothing
 #define TRAIT_RSG_IMMUNE		"rsgimmune" //prevents RSG syringes from piercing your clothing
 
 #define TRAIT_NO_BONES 			"no_bones"
diff --git a/code/_globalvars/traits.dm b/code/_globalvars/traits.dm
index a1f5533f8d2..cf78a9c78dd 100644
--- a/code/_globalvars/traits.dm
+++ b/code/_globalvars/traits.dm
@@ -120,7 +120,8 @@ GLOBAL_LIST_INIT(traits_by_type, list(
 		"TRAIT_OBSCURED_WIRES" = TRAIT_OBSCURED_WIRES,
 		"TRAIT_XENO_INTERACTABLE" = TRAIT_XENO_INTERACTABLE,
 		"TRAIT_NO_THROWN_MESSAGE" = TRAIT_NO_THROWN_MESSAGE,
-		"TRAIT_SILENT_INSERTION" = TRAIT_SILENT_INSERTION
+		"TRAIT_SILENT_INSERTION" = TRAIT_SILENT_INSERTION,
+		"TRAIT_HYPOSPRAY_IMMUNE" = TRAIT_HYPOSPRAY_IMMUNE
 	),
 
 	/turf = list(
diff --git a/code/modules/clothing/spacesuits/ert_hardsuits.dm b/code/modules/clothing/spacesuits/ert_hardsuits.dm
index a15900b1e6a..f59f8ece4d7 100644
--- a/code/modules/clothing/spacesuits/ert_hardsuits.dm
+++ b/code/modules/clothing/spacesuits/ert_hardsuits.dm
@@ -105,6 +105,7 @@
 
 /obj/item/clothing/suit/space/hardsuit/ert/security/Initialize(mapload)
 	. = ..()
+	ADD_TRAIT(src, TRAIT_HYPOSPRAY_IMMUNE, ROUNDSTART_TRAIT)
 	ADD_TRAIT(src, TRAIT_RSG_IMMUNE, ROUNDSTART_TRAIT)
 
 //Engineer
@@ -154,6 +155,7 @@
 
 /obj/item/clothing/suit/space/hardsuit/ert/medical/Initialize(mapload)
 	. = ..()
+	ADD_TRAIT(src, TRAIT_HYPOSPRAY_IMMUNE, ROUNDSTART_TRAIT)
 	ADD_TRAIT(src, TRAIT_RSG_IMMUNE, ROUNDSTART_TRAIT)
 
 //Janitor
diff --git a/code/modules/clothing/spacesuits/hardsuit.dm b/code/modules/clothing/spacesuits/hardsuit.dm
index 185f31f23ff..7fd7d909473 100644
--- a/code/modules/clothing/spacesuits/hardsuit.dm
+++ b/code/modules/clothing/spacesuits/hardsuit.dm
@@ -388,6 +388,7 @@
 
 /obj/item/clothing/suit/space/hardsuit/syndi/elite/sst/Initialize(mapload)
 	. = ..()
+	ADD_TRAIT(src, TRAIT_HYPOSPRAY_IMMUNE, ROUNDSTART_TRAIT)
 	ADD_TRAIT(src, TRAIT_RSG_IMMUNE, ROUNDSTART_TRAIT)
 
 /obj/item/clothing/suit/space/hardsuit/syndi/freedom
diff --git a/code/modules/clothing/spacesuits/misc_spacesuits.dm b/code/modules/clothing/spacesuits/misc_spacesuits.dm
index b411f216e08..c73074e81e1 100644
--- a/code/modules/clothing/spacesuits/misc_spacesuits.dm
+++ b/code/modules/clothing/spacesuits/misc_spacesuits.dm
@@ -65,6 +65,7 @@
 
 /obj/item/clothing/suit/space/deathsquad/Initialize(mapload)
 	. = ..()
+	ADD_TRAIT(src, TRAIT_HYPOSPRAY_IMMUNE, ROUNDSTART_TRAIT)
 	ADD_TRAIT(src, TRAIT_RSG_IMMUNE, ROUNDSTART_TRAIT)
 
 /obj/item/clothing/head/helmet/space/deathsquad/beret
diff --git a/code/modules/mod/mod_types.dm b/code/modules/mod/mod_types.dm
index 7806681f01e..f78359559f6 100644
--- a/code/modules/mod/mod_types.dm
+++ b/code/modules/mod/mod_types.dm
@@ -305,6 +305,10 @@
 		/obj/item/mod/module/jetpack/advanced,
 	)
 
+/obj/item/mod/control/pre_equipped/nuclear/Initialize(mapload, new_theme, new_skin, new_core, new_access)
+	. = ..()
+	ADD_TRAIT(chestplate, TRAIT_HYPOSPRAY_IMMUNE, ROUNDSTART_TRAIT)
+
 /obj/item/mod/control/pre_equipped/elite
 	theme = /datum/mod_theme/elite
 	applied_cell = /obj/item/stock_parts/cell/bluespace
@@ -322,6 +326,10 @@
 		/obj/item/mod/module/jetpack/advanced,
 	)
 
+/obj/item/mod/control/pre_equipped/elite/Initialize(mapload, new_theme, new_skin, new_core, new_access)
+	. = ..()
+	ADD_TRAIT(chestplate, TRAIT_HYPOSPRAY_IMMUNE, ROUNDSTART_TRAIT)
+
 /obj/item/mod/control/pre_equipped/prototype
 	theme = /datum/mod_theme/prototype
 	req_access = list()
diff --git a/code/modules/reagents/reagent_containers/hypospray.dm b/code/modules/reagents/reagent_containers/hypospray.dm
index b37c3078c1a..7a410f66420 100644
--- a/code/modules/reagents/reagent_containers/hypospray.dm
+++ b/code/modules/reagents/reagent_containers/hypospray.dm
@@ -1,7 +1,6 @@
-////////////////////////////////////////////////////////////////////////////////
-/// HYPOSPRAY
-////////////////////////////////////////////////////////////////////////////////
-
+//////////////////////////////
+/// MARK: HYPOSPRAY
+//////////////////////////////
 /obj/item/reagent_containers/hypospray
 	name = "hypospray"
 	desc = "The DeForest Medical Corporation hypospray is a sterile, air-needle autoinjector for rapid administration of drugs to patients."
@@ -15,8 +14,14 @@
 	resistance_flags = ACID_PROOF
 	container_type = OPENCONTAINER
 	slot_flags = SLOT_FLAG_BELT
-	var/ignore_flags = FALSE
+	/// If TRUE, the hypospray can inject through most hardsuits/modsuits.
+	var/can_pierce_hardsuits = FALSE
+	/// If TRUE, the hypospray isn't blocked by suits with TRAIT_HYPOSPRAY_IMMUNE.
+	var/ignore_hypospray_immunity = FALSE
+	/// If TRUE, the hypospray will reject any chemicals not on the safe_chem_list.
 	var/safety_hypo = FALSE
+	// List of SOSHA-approved medicines.
+	/// List of reagents that are allowed to go into a hypospray with active safeties.
 	var/static/list/safe_chem_list = list("antihol", "charcoal", "epinephrine", "insulin", "teporone", "salbutamol", "omnizine",
 									"weak_omnizine", "godblood", "potass_iodide", "oculine", "mannitol", "spaceacillin", "salglu_solution",
 									"sal_acid", "cryoxadone", "sugar", "hydrocodone", "mitocholide", "rezadone", "menthol",
@@ -30,7 +35,12 @@
 	if(!iscarbon(M))
 		return
 
-	if(reagents.total_volume && (ignore_flags || M.can_inject(user, TRUE))) // Ignore flag should be checked first or there will be an error message.
+	var/mob/living/carbon/human/H = M
+	if(HAS_TRAIT(H.wear_suit, TRAIT_HYPOSPRAY_IMMUNE) && !ignore_hypospray_immunity)	// This check is here entirely to stop goobers injecting nukies with meme chems
+		to_chat(user, "<span class='warning'>[src] is unable to penetrate the armour of [M] or interface with any injection ports.</span>")
+		return
+
+	if(reagents.total_volume && (can_pierce_hardsuits || M.can_inject(user, TRUE))) // can_pierce_hardsuits should be checked first or there will be an error message.
 		to_chat(M, "<span class='warning'>You feel a tiny prick!</span>")
 		to_chat(user, "<span class='notice'>You inject [M] with [src].</span>")
 
@@ -88,10 +98,13 @@
 /obj/item/reagent_containers/hypospray/emag_act(mob/user)
 	if(safety_hypo && !emagged)
 		emagged = TRUE
-		ignore_flags = TRUE
+		can_pierce_hardsuits = TRUE
 		to_chat(user, "<span class='warning'>You short out the safeties on [src].</span>")
 		return TRUE
 
+//////////////////////////////
+// MARK: HYPO VARIANTS
+//////////////////////////////
 /obj/item/reagent_containers/hypospray/safety
 	name = "medical hypospray"
 	desc = "A general use medical hypospray for quick injection of chemicals. There is a safety button by the trigger."
@@ -103,32 +116,40 @@
 	icon_state = "ert_hypo"
 	list_reagents = list("omnizine" = 30)
 
+/obj/item/reagent_containers/hypospray/combat
+	name = "combat stimulant injector"
+	desc = "A modified air-needle autoinjector, used by support operatives to quickly heal injuries in combat. It has a proprietary adapter allowing it to inject through the ports of Syndicate-made hardsuits."
+	amount_per_transfer_from_this = 15
+	possible_transfer_amounts = null
+	icon_state = "combat_hypo"
+	volume = 90
+	can_pierce_hardsuits = TRUE // So they can heal their comrades.
+	ignore_hypospray_immunity = TRUE
+	list_reagents = list("epinephrine" = 30, "weak_omnizine" = 30, "salglu_solution" = 30)
+
+/obj/item/reagent_containers/hypospray/combat/nanites
+	desc = "A modified air-needle autoinjector for use in combat situations. Prefilled with expensive medical nanites for rapid healing. It can interface with the injection ports on any type of hardsuit."
+	icon_state = "nanites_hypo"
+	volume = 100
+	list_reagents = list("nanites" = 100)
+
+//////////////////////////////
+// MARK: CMO HYPO
+//////////////////////////////
 /obj/item/reagent_containers/hypospray/CMO
 	name = "advanced hypospray"
 	list_reagents = list("omnizine" = 30)
+	volume = 100
+	can_pierce_hardsuits = TRUE
 	resistance_flags = INDESTRUCTIBLE | LAVA_PROOF | FIRE_PROOF | ACID_PROOF
 
 /obj/item/reagent_containers/hypospray/CMO/Initialize(mapload)
 	. = ..()
 	RegisterSignal(src, COMSIG_PARENT_QDELETING, PROC_REF(alert_admins_on_destroy))
 
-/obj/item/reagent_containers/hypospray/combat
-	name = "combat stimulant injector"
-	desc = "A modified air-needle autoinjector, used by support operatives to quickly heal injuries in combat."
-	amount_per_transfer_from_this = 15
-	possible_transfer_amounts = null
-	icon_state = "combat_hypo"
-	volume = 90
-	ignore_flags = 1 // So they can heal their comrades.
-	list_reagents = list("epinephrine" = 30, "weak_omnizine" = 30, "salglu_solution" = 30)
-
-/obj/item/reagent_containers/hypospray/combat/nanites
-	desc = "A modified air-needle autoinjector for use in combat situations. Prefilled with expensive medical nanites for rapid healing."
-	icon_state = "nanites_hypo"
-	volume = 100
-	list_reagents = list("nanites" = 100)
-
-/// This is an empty variant
+//////////////////////////////
+// MARK: AUTOINJECTOR
+//////////////////////////////
 /obj/item/reagent_containers/hypospray/autoinjector
 	name = "empty autoinjector"
 	desc = "A rapid and safe way to inject chemicals into humanoids. This one is empty."
@@ -138,7 +159,8 @@
 	amount_per_transfer_from_this = 10
 	possible_transfer_amounts = null
 	volume = 10
-	ignore_flags = TRUE //so you can medipen through hardsuits
+	can_pierce_hardsuits = TRUE //so you can medipen through hardsuits
+	ignore_hypospray_immunity = TRUE
 	container_type = DRAWABLE
 	flags = null