diff --git a/code/_globalvars/lists/reagents.dm b/code/_globalvars/lists/reagents.dm
index 8417275d780..23d310be857 100644
--- a/code/_globalvars/lists/reagents.dm
+++ b/code/_globalvars/lists/reagents.dm
@@ -58,4 +58,9 @@ var/global/list/blocked_chems = list("polonium", "initropidril", "concentrated_i
 							"reagent", "life","dragonsbreath")
 
 //List of chems/mixtures that can't grow in plants (in addition to the global random chem blacklist)
-var/global/list/plant_blocked_chems = list()	//filled in /datum/reagents/New() with chems that have can_grow_in_plants = 0
\ No newline at end of file
+var/global/list/plant_blocked_chems = list()	//filled in /datum/reagents/New() with chems that have can_grow_in_plants = 0
+
+var/global/list/safe_chem_list = list("antihol", "charcoal", "epinephrine", "insulin", "teporone","silver_sulfadiazine", "salbutamol",
+									  "omnizine", "stimulants", "synaptizine", "potass_iodide", "oculine", "mannitol", "styptic_powder",
+									  "spaceacillin", "salglu_solution", "sal_acid", "cryoxadone", "blood", "synthflesh", "hydrocodone",
+									  "mitocholide", "rezadone")
\ No newline at end of file
diff --git a/code/modules/reagents/Chemistry-Machinery.dm b/code/modules/reagents/Chemistry-Machinery.dm
index 68bcd9306d3..b0200b22ab2 100644
--- a/code/modules/reagents/Chemistry-Machinery.dm
+++ b/code/modules/reagents/Chemistry-Machinery.dm
@@ -625,13 +625,17 @@
 				if(!name)
 					return
 				name = reject_bad_text(name)
-				while (count--)
+				var/is_medical_patch = chemical_safety_check(reagents)
+				while(count--)
 					var/obj/item/weapon/reagent_containers/food/pill/patch/P = new/obj/item/weapon/reagent_containers/food/pill/patch(src.loc)
 					if(!name) name = reagents.get_master_reagent_name()
 					P.name = "[name] patch"
 					P.pixel_x = rand(-7, 7) //random position
 					P.pixel_y = rand(-7, 7)
 					reagents.trans_to(P,amount_per_patch)
+					if(is_medical_patch)
+						P.instant_application = 1
+						P.icon_state = "bandaid_med"
 		else if (href_list["createbottle"])
 			if(!condi)
 				var/name = input(usr,"Name:","Name your bottle!",reagents.get_master_reagent_name()) as text|null
@@ -757,6 +761,12 @@
 	else
 		return 0
 
+/obj/machinery/chem_master/proc/chemical_safety_check(datum/reagents/R)
+	var/all_safe = 1
+	for(var/datum/reagent/A in R.reagent_list)
+		if(!safe_chem_list.Find(A.id))
+			all_safe = 0
+	return all_safe
 
 /obj/machinery/chem_master/condimaster
 	name = "\improper CondiMaster 3000"
diff --git a/code/modules/reagents/newchem/patch.dm b/code/modules/reagents/newchem/patch.dm
index 793b6f8ae6f..f686d293c24 100644
--- a/code/modules/reagents/newchem/patch.dm
+++ b/code/modules/reagents/newchem/patch.dm
@@ -36,6 +36,7 @@
 /obj/item/weapon/reagent_containers/food/pill/patch/synthflesh
 	name = "syntheflesh patch"
 	desc = "Helps with burn injuries."
+	icon_state = "bandaid_med"
 	instant_application = 1
 
 /obj/item/weapon/reagent_containers/food/pill/patch/synthflesh/New()
diff --git a/icons/obj/chemical.dmi b/icons/obj/chemical.dmi
index ccf3bad52b5..40f5b5ddc17 100644
Binary files a/icons/obj/chemical.dmi and b/icons/obj/chemical.dmi differ