diff --git a/code/modules/reagents/chemistry/reagents/medicine_reagents.dm b/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
index 53320e9460..b8e91c2da8 100644
--- a/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
+++ b/code/modules/reagents/chemistry/reagents/medicine_reagents.dm
@@ -152,7 +152,37 @@
 /datum/reagent/medicine/clonexadone/on_mob_life(mob/living/M)
 	if(M.bodytemperature < T0C)
 		M.adjustCloneLoss(0.00006 * (M.bodytemperature ** 2) - 6, 0)
-		M.status_flags &= ~DISFIGURED
+		M.remove_trait(TRAIT_DISFIGURED, TRAIT_GENERIC)
+		. = 1
+	metabolization_rate = REAGENTS_METABOLISM * (0.000015 * (M.bodytemperature ** 2) + 0.75)
+	..()
+
+/datum/reagent/medicine/pyroxadone
+	name = "Pyroxadone"
+	id = "pyroxadone"
+	description = "A mixture of cryoxadone and slime jelly, that apparently inverses the requirement for its activation."
+	color = "#f7832a"
+	taste_description = "spicy jelly"
+
+/datum/reagent/medicine/pyroxadone/on_mob_life(mob/living/M)
+	if(M.bodytemperature > BODYTEMP_HEAT_DAMAGE_LIMIT)
+		var/power = 0
+		switch(M.bodytemperature)
+			if(BODYTEMP_HEAT_DAMAGE_LIMIT to 400)
+				power = 2
+			if(400 to 460)
+				power = 3
+			else
+				power = 5
+		if(M.on_fire)
+			power *= 2
+
+		M.adjustOxyLoss(-2 * power, 0)
+		M.adjustBruteLoss(-power, 0)
+		M.adjustFireLoss(-1.5 * power, 0)
+		M.adjustToxLoss(-power, 0, TRUE)
+		M.adjustCloneLoss(-power, 0)
+		M.remove_trait(TRAIT_DISFIGURED, TRAIT_GENERIC)
 		. = 1
 	metabolization_rate = REAGENTS_METABOLISM * (0.000015 * (M.bodytemperature ** 2) + 0.75)
 	..()
@@ -1167,6 +1197,14 @@
 
 	..()
 
+/datum/reagent/medicine/ketrazine/on_mob_add(mob/living/M)
+	M.add_trait(TRAIT_IGNORESLOWDOWN, id)
+	M.add_trait(TRAIT_GOTTAGOFAST, id)
+
+/datum/reagent/medicine/ketrazine/on_mob_delete(mob/living/M)
+	M.remove_trait(TRAIT_IGNORESLOWDOWN, id)
+	M.remove_trait(TRAIT_GOTTAGOFAST, id)
+
 /datum/reagent/medicine/ketrazine/overdose_process(mob/living/M)
 	if(prob(66))
 		to_chat(M, "<span class='warning'> You feel a sense of impending doom. </span>")