diff --git a/code/modules/research/nanites/nanite_chamber.dm b/code/modules/research/nanites/nanite_chamber.dm
index 01513a0b41..8675d54b46 100644
--- a/code/modules/research/nanites/nanite_chamber.dm
+++ b/code/modules/research/nanites/nanite_chamber.dm
@@ -41,12 +41,12 @@
 	update_icon()
 
 /obj/machinery/nanite_chamber/proc/set_safety(threshold)
-	if(!occupant)
+	if(!occupant || SEND_SIGNAL(occupant, COMSIG_NANITE_CHECK_CONSOLE_LOCK))
 		return
 	SEND_SIGNAL(occupant, COMSIG_NANITE_SET_SAFETY, threshold)
 
 /obj/machinery/nanite_chamber/proc/set_cloud(cloud_id)
-	if(!occupant)
+	if(!occupant || SEND_SIGNAL(occupant, COMSIG_NANITE_CHECK_CONSOLE_LOCK))
 		return
 	SEND_SIGNAL(occupant, COMSIG_NANITE_SET_CLOUD, cloud_id)
 
@@ -82,7 +82,7 @@
 		return
 	if((stat & MAINT) || panel_open)
 		return
-	if(!occupant || busy)
+	if(!occupant || busy || SEND_SIGNAL(occupant, COMSIG_NANITE_CHECK_CONSOLE_LOCK))
 		return
 
 	var/locked_state = locked
@@ -173,7 +173,6 @@
 		return FALSE
 
 	..()
-
 	return TRUE
 
 /obj/machinery/nanite_chamber/relaymove(mob/user as mob)
diff --git a/code/modules/research/nanites/nanite_chamber_computer.dm b/code/modules/research/nanites/nanite_chamber_computer.dm
index 70e4d05590..f69cb58456 100644
--- a/code/modules/research/nanites/nanite_chamber_computer.dm
+++ b/code/modules/research/nanites/nanite_chamber_computer.dm
@@ -50,6 +50,10 @@
 		data["status_msg"] = chamber.busy_message
 		return data
 
+	if(SEND_SIGNAL(L, COMSIG_NANITE_CHECK_CONSOLE_LOCK))
+		data["status_msg"] = "Error: Nanite keycodes scrambled. Unable to operate."
+		return data
+
 	data["status_msg"] = null
 	data["scan_level"] = chamber.scan_level
 	data["locked"] = chamber.locked